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KMID : 1038120210540030390
Clinical Endoscopy
2021 Volume.54 No. 3 p.390 ~ p.396
Dedicated Cold Snare vs. Traditional Snare for Polypectomy of Diminutive and Small Lesions in a Porcine Model: A Research Group for Endoscopic Instruments and Stents (REIS) Study
Lee Han-Hee

Lee Bo-In
Kim Jung-Wook
Lim Hyun
Lee Si-Hyung
Cho Jun-Hyung
Jung Yun-Ho
Kim Kyoung-Oh
Kim Chan-Gyoo
Lee Kee-Myung
Park Jong-Jae
Choi Myung-Gyu
Chun Hoon-Jai
Kim Ho-Gak
Abstract
Background/Aims: The aim of this in vivo animal study was to evaluate the effectiveness and safety of dedicated cold snare (DCS) compared with those of traditional snare (TS) for cold snare polypectomy (CSP).

Methods: A total of 36 diminutive (5 mm) and 36 small (9 mm) pseudolesions were made by electrocoagulation in the colons of mini-pigs.

Results: For the diminutive lesions, there were no significant differences in technical success rate, procedure time, or complete resection rate between the DCS and TS groups; the rate of uneven resection margin in the DCS group was significantly lower than that of the TS group. For small lesions, technical success rate and complete resection rate were significantly higher in the DCS group than in the TS group (100% [18/18] vs. 55.6% [10/18], p=0.003; 94.4% [17/18] vs. 40% [4/10], p=0.006). In addition, the procedure duration was significantly shorter, and the rate of uneven resection margin was significantly lower in the DCS group (28.5 sec vs. 66.0 sec, p=0.006; 11.1% [2/18] vs. 100% [10/10], p<0.001). Two cases of perforation occurred in the DCS group. Multivariate analysis revealed that DCS use was independently associated with complete resection.

Conclusions: DCS is superior to TS in terms of technical success, complete resection, and reducing the duration of the procedure for CSP of small polyps.
KEYWORD
Animal model, Cold snare polypectomy, Colonic polyps, Dedicated cold snare, Perforation
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